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Article

Association between CTLA4 polymorphisms and susceptibility to granulomatosis with polyangiitis.

International reviews of immunology - 1 Jan 2025

Mohamadi Amirhosein, Ehtesham Naeim, Hashemi Huriyeh, Ansari Narges, Zavar Mohammad Javad, Mousavi Seyyed Hossein, Eskandari Neda, Zarei Mahboobeh, Khodabandehloo Fatemeh

Abstract excerpt

BACKGROUND: Granulomatosis with polyangiitis (GPA) is an autoimmune condition. This study evaluated the relationship between CTLA4 gene polymorphisms, specifically rs231775, rs5742909, and rs3087243, and the risk of developing GPA. MATERIALS AND METHODS: A case-control study was conducted with 217 participants, 102 individuals diagnosed with GPA, and 115 control subjects. The high-resolution melting (HRM)...

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Identifiers

PMID: 40772772
DOI: 10.1080/08830185.2025.2543084

Genes

CTLA4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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