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Article

Increased reactive oxygen species production and p47phox phosphorylation in neutrophils from myeloproliferative disorders patients with JAK2 (V617F) mutation.

Haematologica - 1 Oct 2013

Hurtado-Nedelec Margarita, Csillag-Grange Marie-José, Boussetta Tarek, Belambri Sahra Amel, Fay Michèle, Cassinat Bruno, Gougerot-Pocidalo Marie-Anne, Dang Pham My-Chan, El-Benna Jamel

Abstract excerpt

Myeloproliferative disorders are associated with increased risk of thrombosis and vascular complications. The pathogenesis of these complications is not completely known. Reactive oxygen species produced by the neutrophil NADPH oxidase could have a role in this process. The aim of this study was...

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Source

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Identifiers

PMID: 23975181
DOI: 10.3324/haematol.2012.082560
PMCID: PMC3789455

Genes

JAK2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23975181-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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