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Article

NADPH Oxidases as Therapeutic Targets in Chronic Myelogenous Leukemia

16 May 2014

Abstract excerpt

PURPOSE: Cancer cells show higher levels of reactive oxygen species (ROS) than normal cells and increasing intracellular ROS levels are becoming a recognized strategy against tumor cells. Thus, diminishing ROS levels could be also detrimental to cancer cells. We surmise that avoiding ROS generation would be a better option than quenching ROS with antioxidants. Chronic myelogenous leukemia (CML) is triggered by...

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Share to Chronic Myeloid Leukemia Treatments
Share to Neutrophil, Myeloperoxidase and Oxidative Mechanisms
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PMID: 24833663
DOI: 10.1158/1078-0432.ccr-13-3044

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