Article
Nitric oxide derivatives and soluble plasma selectins in patients with myeloproliferative neoplasms.
Thrombosis and haemostasis - 1 Jul 2010
Cella Giuseppe, Marchetti Marina, Vianello Fabrizio, Panova-Noeva Marina, Vignoli Alfonso, Russo Laura, Barbui Tiziano, Falanga Anna
Abstract excerpt
Essential thrombocythaemia (ET) and polycythaemia vera (PV) are characterised by a high incidence of thrombotic complications due to high-shear stress of the vessel wall, blood hyperviscosity and hypoxaemia, all factors responsible for chronic endothelial dysfunction and platelet and leukocyte activation. We evaluated the activation status of vascular cells in 18 consecutive ET and 14 PV patients by measuring the...
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