Excessive function of peripheral blood neutrophils from patients with Behçet's disease and from HLA-B51 transgenic mice.

doi:10.1002/art.1780380321

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Article

Excessive function of peripheral blood neutrophils from patients with Behçet's disease and from HLA-B51 transgenic mice.

Arthritis and rheumatism - 1 Mar 1995

Takeno M, Kariyone A, Yamashita N, Takiguchi M, Mizushima Y, Kaneoka H, Sakane T

Abstract excerpt

OBJECTIVE: To elucidate the role played by HLA-B51 in the neutrophil hyperfunction of Behçet's disease, we determined the superoxide production by purified peripheral blood neutrophils from Behçet's disease patients, from HLA-B51 positive healthy individuals, and from HLA-B51 transgenic mice. MET...

Topics

Animals
Behcet Syndrome
Female
Flow Cytometry
HLA-B Antigens
HLA-B51 Antigen
Humans
Male
Mice
Mice, Inbred C3H
Mice, Transgenic
Neutrophils
Phenotype
Superoxides

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