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Article

Contribution of protein Z and protein Z-dependent protease inhibitor in generalized Shwartzman reaction.

Critical care medicine - 1 Dec 2013

Butschkau Antje, Nagel Philipp, Grambow Eberhard, Zechner Dietmar, Broze George J, Vollmar Brigitte

Abstract excerpt

OBJECTIVE: Sepsis, a leading cause of mortality in critically ill patients, is closely linked to the excessive activation of coagulation and inflammation. Protein Z, a cofactor for the protein Z-dependent protease inhibitor, enhances the inhibition of coagulation factor Xa, and protein Z-dependent protease inhibitor inhibits factor XIa in a protein Z-independent fashion. The functions of protein Z and protein...

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Identifiers

PMID: 23963134
DOI: 10.1097/CCM.0b013e318298a562
PMCID: PMC3841229

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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