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Article

Prothrombotic phenotype of protein Z deficiency.

Proceedings of the National Academy of Sciences of the United States of America - 6 Jun 2000

Yin Z F, Huang Z F, Cui J, Fiehler R, Lasky N, Ginsburg D, Broze G J

Abstract excerpt

Protein Z (PZ) is a vitamin K-dependent plasma protein whose function has been uncertain. The structure of PZ is very similar to that of the coagulation-related factors VII, IX, and X and PC, but PZ differs from these other proteins in that it is not the zymogen of a serine protease. We have shown recently that PZ forms a calcium ion-dependent complex with activated factor X at phospholipid surfaces and that this...

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Identifiers

PMID: 10829076
DOI: 10.1073/pnas.120081897
PMCID: PMC18721

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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