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Article

Acute inflammation is exacerbated in mice genetically predisposed to a severe protein C deficiency.

Blood - 1 Mar 2007

Lay Angelina J, Donahue Deborah, Tsai Meng-Ju, Castellino Francis J

Abstract excerpt

The anticoagulant, activated protein C (aPC), possesses antithrombotic, profibrinolytic, anti-inflammatory, and antiapoptotic properties, and the level of this protein is an important marker of acute inflammatory responses. Although infusion of aPC improves survival in a subset of patients with s...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 17047151
DOI: 10.1182/blood-2006-07-037945
PMCID: PMC1801051

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17047151-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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