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Article

FUT2 and FUT3 genotype determines CA19-9 cut-off values for detection of cholangiocarcinoma in patients with primary sclerosing cholangitis.

Journal of hepatology - 1 Dec 2013

Wannhoff Andreas, Hov Johannes Roksund, Folseraas Trine, Rupp Christian, Friedrich Kilian, Anmarkrud Jarl Andreas, Weiss Karl Heinz, Sauer Peter, Schirmacher Peter, Boberg Kirsten Muri, Stremmel Wolfgang, Karlsen Tom Hemming, Gotthardt Daniel Nils

Abstract excerpt

BACKGROUND & AIMS: Allelic variants of fucosyltransferases 2 and 3 (FUT2/3) influence serum levels of CA19-9, a screening parameter commonly used for detection of biliary malignancy in PSC. We aimed at improving diagnostic accuracy of CA19-9 by determining the impact of FUT2/3 genotypes. METHODS: CA19-9 levels were measured in 433 PSC patients, 41 of whom had biliary malignancy. Genotypes for FUT3 and FUT2 were...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23958938
DOI: 10.1016/j.jhep.2013.08.005

Genes

FUT2
FUT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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