Potential Biomarkers in Lewis Negative Patients With Pancreatic Cancer.

doi:10.1097/SLA.0000000000001741

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Article

Potential Biomarkers in Lewis Negative Patients With Pancreatic Cancer.

Annals of surgery - 1 Apr 2017

Luo Guopei, Liu Chen, Guo Meng, Cheng He, Lu Yu, Jin Kaizhou, Liu Liang, Long Jiang, Xu Jin, Lu Renquan, Ni Quanxing, Yu Xianjun

Abstract excerpt

OBJECTIVE: To examine potential biomarkers in Lewis negative patients with pancreatic cancer. BACKGROUND: Carbohydrate antigen 19-9 (CA19-9) is currently the most important and widely used biomarker in pancreatic cancer. However, approximately 5 to 10% of the population are Lewis negative individuals, and they are documented to have scarce or no CA19-9 secretion. Therefore, it is necessary to explore potential...

Topics

Adult
Aged
Analysis of Variance
Biomarkers, Tumor
CA-125 Antigen
CA-19-9 Antigen
Case-Control Studies
Databases, Factual
Disease-Free Survival
Female
Genotype
Humans
Kaplan-Meier Estimate
Male

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Middle Aged

Pancreatic Neoplasms

Proportional Hazards Models

Prospective Studies

Source

Open in PubMed

Identifiers

PMID: 28267695
DOI: 10.1097/SLA.0000000000001741

Genes

AFP
FUT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.