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Article

Association of Ulcerative Colitis with FUT2 and FUT3 Polymorphisms in Patients from Southeast China.

PloS one - 1 Jan 2016

Hu Dingyuan, Zhang Daguan, Zheng Shuzi, Guo Maodong, Lin Xinxin, Jiang Yi

Abstract excerpt

OBJECTIVES: Dysbiosis of intestinal microbiota has been implicated in ulcerative colitis (UC). Fucosyltransferase (FUT) 2 and FUT3 determine expression of histo-blood group antigens in the gut and may affect the intestinal microbiota. We investigated the association between FUT2 and FUT3 polymorphisms and UC in Chinese patients. METHODS: We genotyped FUT2 (rs281377, rs1047781 and rs601338) and FUT3 (rs28362459,...

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Share to Case-Control Studies
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Share to Fucosyltransferases
Share to Galactoside 2-alpha-L-fucosyltransferase
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Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 26766790
DOI: 10.1371/journal.pone.0146557
PMCID: PMC4713070

Genes

FUT3
FUT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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