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Article

Associations of FUT2 and FUT3 gene polymorphisms with Crohn's disease in Chinese patients.

Journal of gastroenterology and hepatology - 1 Oct 2014

Hu Ding-yuan, Shao Xiao-xiao, Xu Chang-long, Xia Sheng-long, Yu Li-qin, Jiang Li-jia, Jin Jie, Lin Xiu-qing, Jiang Yi

Abstract excerpt

BACKGROUND AND AIM: FUT2 and FUT3 genes are responsible for the formation of histo-blood group antigens, which act as binding sites for some intestinal microbes. Several studies suggested that FUT2 gene might affect the intestinal microbiota composition and modulate innate immune responses. However, the effect of FUT2 polymorphisms on Crohn's disease (CD) is uncertain. Our study aimed to analyze associations of...

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Source

Identifiers

PMID: 24720527
DOI: 10.1111/jgh.12599

Genes

FUT2
FUT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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