Article
Fut2 genotype is a risk factor for dominant stenosis and biliary candida infections in primary sclerosing cholangitis.
Alimentary pharmacology & therapeutics - 1 Apr 2014
Rupp C, Friedrich K, Folseraas T, Wannhoff A, Bode K A, Weiss K-H, Schirmacher P, Sauer P, Stremmel W, Gotthardt D N
Abstract excerpt
BACKGROUND: A recent genome-wide association study identified the FUT2 secretor status and genotype defined by the single-nucleotide polymorphism rs601338 as potential genetic risk factor in primary sclerosing cholangitis (PSC), which significantly influences biliary bacterial composition. AIM: To determine the impact of the rs601338-FUT2 genotype on frequency of biliary infections, development of dominant...
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