A genome wide association study of genetic loci that influence tumour biomarkers cancer antigen 19-9, carcinoembryonic antigen and α fetoprotein and their associations with cancer risk.

doi:10.1136/gutjnl-2012-303434

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

A genome wide association study of genetic loci that influence tumour biomarkers cancer antigen 19-9, carcinoembryonic antigen and α fetoprotein and their associations with cancer risk.

Gut - 1 Jan 2014

He Meian, Wu Chen, Xu Jianfeng, Guo Huan, Yang Handong, Zhang Xiaomin, Sun Jielin, Yu Dianke, Zhou Li, Peng Tao, He Yunfeng, Gao Yong, Yuan Jing, Deng Qifei, Dai Xiayun, Tan Aihua, Feng Yingying, Zhang Haiying, Min Xinwen, Yang Xiaobo, Zhu Jiang, Zhai Kan, Chang Jiang, Qin Xue, Tan Wen, Hu Yanling, Lang Mingjian, Tao Sha, Li Yuanfeng, Li Yi, Feng Junjie, Li Dongfeng, Kim Seong-Tae, Zhang Shijun, Zhang Hongxing, Zheng S Lilly, Gui Lixuan, Wang Youjie, Wei Sheng, Wang Feng, Fang Weimin, Liang Yuan, Zhai Yun, Chen Weihong, Miao Xiaoping, Zhou Gangqiao, Hu Frank B, Lin Dongxin, Mo Zengnan, Wu Tangchun

Abstract excerpt

OBJECTIVE: Tumour biomarkers are used as indicators for cancer screening and as predictors for therapeutic responses and prognoses in cancer patients. We aimed to identify genetic loci that influence concentrations of cancer antigen 19-9 (CA19-9), carcinoembryonic antigen (CEA) and α fetoprotein (AFP), and investigated the associations between the significant single nucleotide polymorphisms (SNPs) with risks of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to alpha-Fetoproteins

Share to CA-19-9 Antigen

Share to Carcinoembryonic Antigen

Share to Carcinoma

Share to Carcinoma, Hepatocellular

Share to Esophageal Neoplasms

Share to Linear Models

Share to Pancreatic Neoplasms

Source

Open in PubMed

Identifiers

PMID: 23300138
DOI: 10.1136/gutjnl-2012-303434

Genes

AFP
ABO
FUT2
FUT6
FUT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A genome wide association study of genetic loci that influence tumour biomarkers cancer antigen 19-9, carcinoembryonic antigen and α fetoprotein and their associations with cancer risk.PMID 23300138Read ↗

Gene Variants That Affect Levels of Circulating Tumor Markers Increase Identification of Patients With Pancreatic CancerSemantic proximity Read ↗

Common and Rare Sequence Variants Influencing Tumor Biomarkers in Blood.Semantic proximity Read ↗

A New CA19-9 Cutoff Value Identifies Lewis Antigen Status and Refines Prognostic Stratification in PDAC.Semantic proximity Read ↗

Optimize CA19-9 in detecting pancreatic cancer by Lewis and Secretor genotyping.Semantic proximity Read ↗

Using Tumor Marker Gene Variants to Improve the Diagnostic Accuracy of DUPAN-2 and Carbohydrate Antigen 19-9 for Pancreatic Cancer.Semantic proximity Read ↗

New observations on the utility of CA19-9 as a biomarker in Lewis negative patients with pancreatic cancer.Semantic proximity Read ↗

Potential Biomarkers in Lewis Negative Patients With Pancreatic Cancer.Semantic proximity Read ↗

Quantitative assessment of polymorphisms in H19 lncRNA and cancer risk: a meta-analysis of 13,392 cases and 18,893 controls.Semantic proximity Read ↗

The influence of LncRNA H19 polymorphic variants on susceptibility to cancer: A systematic review and updated meta-analysis of 28 case-control studies.Semantic proximity Read ↗

Association between cancer antigen 19-9 and diabetes risk: A prospective and Mendelian randomization study.Semantic proximity Read ↗

Genetic Variation at 19q13.33 confers colorectal cancer risk through the interaction of mucosal expression of FUT2 and plasma vitamin B12 levelsSemantic proximity Read ↗

Genetic variations affecting serum carcinoembryonic antigen levels and status of regional lymph nodes in patients with sporadic colorectal cancer from Southern China.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.