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Article

New observations on the utility of CA19-9 as a biomarker in Lewis negative patients with pancreatic cancer.

Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] - 1 Dec 2018

Luo Guopei, Fan Zhiyao, Cheng He, Jin Kaizhou, Guo Meng, Lu Yu, Yang Chao, Fan Kun, Huang Qiuyi, Long Jiang, Liu Liang, Xu Jin, Lu Renquan, Ni Quanxing, Warshaw Andrew L, Liu Chen, Yu Xianjun

Abstract excerpt

BACKGROUND: Carbohydrate antigen 19-9 (CA19-9) is the best-validated biomarker for pancreatic cancer. The National Comprehensive Cancer Network (NCCN) guideline asserts that "CA19-9 will be undetectable in Lewis antigen-negative individuals". However, reports of CA19-9 secretion and its significance in Lewis (-) patients with pancreatic cancer have been inconsistent. This study was to examine serum CA19-9 levels...

Topics

Aged
Biomarkers, Tumor
CA-19-9 Antigen
Female
Fucosyltransferases
Genotype
Humans
Male
Middle Aged
Pancreatic Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Pancreatic Neoplasms

Survival Analysis

Source

Identifiers

PMID: 30131287
DOI: 10.1016/j.pan.2018.08.003

Genes

FUT3

Provenance

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