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Article

LAIR-1 activation inhibits inflammatory macrophage phenotype in vitro.

Cellular immunology - 1 Sept 2018

Jin Jingyi, Wang Ying, Ma Qianli, Wang Ning, Guo Wenwei, Jin Boquan, Fang Liang, Chen Lihua

Abstract excerpt

Macrophages are key cell types of innate immunity and play a central role in inflammation and host defense. Leukocyte-associated Ig-like receptor-1 (LAIR-1) is highly expressed on macrophages and regulates macrophage functions in several conditions. However, whether LAIR-1 is involved in governing macrophage polarization is still not clear. Here, we investigated the effect of LAIR-1 on macrophage polarization...

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Identifiers

PMID: 29887420
DOI: 10.1016/j.cellimm.2018.05.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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