Article
A Novel Anti-inflammatory Phenotype Transformed by Repetitive Low-dose Lipopolysaccharide in Primary Peritoneal Tissue-resident Macrophages.
Anticancer research - 1 Aug 2020
Mizobuchi Haruka, Yamamoto Kazushi, Yamashita Masafumi, Inagawa Hiroyuki, Kohchi Chie, Soma Gen-Ichiro
Abstract excerpt
BACKGROUND/AIM: Our previous studies suggested that oral administration of lipopolysaccharide (LPS) regulates the progression of various diseases via transformation of tissue-resident macrophages (MΦ). Recently, we characterized microglia transformed by repetitive low-dose LPS treatment (REPELL-microglia) in vitro, and this response was similar to that observed in response to oral administration of LPS in vivo....
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