Article
Expression and secretion of galectin-12 in the context of neutrophilic differentiation of human promyeloblastic HL-60 cells.
Journal of cellular physiology - 1 Jun 2024
Tazhitdinova Rada, Cristiano Sara, Yi Joshua, Zhurov Vladimir, DeKoter Rodney P, Timoshenko Alexander V
Abstract excerpt
Galectin-12 is a tissue-specific galectin that has been largely defined by its role in the regulation of adipocyte differentiation and lipogenesis. This study aimed to evaluate the role of galectin-12 in the differentiation and polarization of neutrophils within a model of acute myeloid leukemia HL-60 cells. All-trans retinoic acid and dimethyl sulfoxide were used to induce differentiation of HL-60 cells which...
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