Article
Low density receptor-related protein 1 (LRP1) promotes anti-inflammatory phenotype in murine macrophages.
Cell and tissue research - 1 Dec 2013
May Petra, Bock Hans H, Nofer Jerzy-Roch
Abstract excerpt
We have previously reported that apolipoprotein E (apoE), a protein component of very-low-density lipoproteins (VLDL) and high-density lipoproteins and a potent plasma-borne atheroprotective factor, exerts anti-inflammatory activity in macrophages by switching the activation profile from M1 ("classic") to M2 ("alternative") in a process involving signaling via low-density lipoprotein receptor (LDLR) family...
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