Article
Human angiotensinogen +11525 C/A polymorphism modulates its gene expression through microRNA binding.
Physiological genomics - 1 Oct 2013
Mopidevi Brahmaraju, Ponnala Madhusudhan, Kumar Ashok
Abstract excerpt
Hypertension is a serious risk factor for cardiovascular disease. Like other complex disease, hypertension is caused by a combination of genetic and environmental factors. The renin-angiotensin system plays an important role in the regulation of blood pressure. Angiotensinogen (AGT) gene is associated with essential hypertension in Caucasians, Japanese, and Asian-Indian subjects. AGT gene may also be associated...
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