Article

Analysis of the Combined Effect of rs699 and rs5051 on Angiotensinogen Expression and Hypertension

2023-04-08

Abstract excerpt

<h4>ABSTRACT</h4> Hypertension (HTN) involves genetic variability in the renin-angiotensin system and characterizing this variability will help advance precision antihypertensive treatments. We previously reported that angiotensinogen ( AGT ) mRNA is endogenously bound by mir-122-5p and that rs699 A>G significantly decreases reporter mRNA in the functional mirSNP assay PASSPORT-seq. The AGT promoter variant rs5...

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Literature Corpus work: a7cc6167-64c0-5044-af28-5a1f77f0fa79
DOI: 10.1101/2023.04.07.536073

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