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Article

A haplotype of human angiotensinogen gene containing -217A increases blood pressure in transgenic mice compared with -217G.

American journal of physiology. Regulatory, integrative and comparative physiology - 1 Dec 2008

Jain Sudhir, Vinukonda Govindaiah, Fiering Steven N, Kumar Ashok

Abstract excerpt

The human angiotensinogen (hAGT) gene contains an A/G polymorphism at -217, and frequency of -217A allele is increased in African-American hypertensive patients. The hAGT gene has seven polymorphic sites in the 1.2-kb region of its promoter, and variant -217A almost always occurs with -532T, -793...

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Identifiers

PMID: 18945948
DOI: 10.1152/ajpregu.90637.2008
PMCID: PMC2685293

Genes

AGT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18945948-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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