Article
Human aldosterone synthase gene polymorphism promotes miRNA binding and regulates gene expression.
Physiological genomics - 15 Dec 2014
Maharjan Shreekrishna, Mopidevi Brahmaraju, Kaw Meenakshi Kaul, Puri Nitin, Kumar Ashok
Abstract excerpt
Hypertension is a serious risk factor for myocardial infarction, heart failure, vascular disease, stroke, and renal failure. Like other complex diseases, hypertension is caused by a combination of genetic and environmental factors. The renin-angiotensin-aldosterone system plays an important role in the regulation of blood pressure. The octapeptide angiotensin II (ANG II) is one of the most active vasopressor...
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