Article
Peripheral T-cell lymphoma emerging in a patient with aggressive polymyositis: molecular evidence for neoplastic transformation of an oligoclonal T-cell infiltrate.
Acta neuropathologica - 1 Oct 2013
Tsankova Nadejda M, Bevan Carolyn, Jobanputra Vaidehi, Ko Yen Chen Kevin, Mayer Elizabeth W, Lefkowitch Jay H, Mansukhani Mahesh, Rowland Lewis P, Bhagat Govind, Tanji Kurenai
Abstract excerpt
We report a rare case of peripheral T-cell lymphoma arising in a 52-year-old man with biopsy-proven aggressive polymyositis, who had cardiac involvement, progressive bulbar symptoms, and died 11 months post diagnosis due to multiorgan failure. Using a multimodality approach including immunohistochemistry, genome-wide single nucleotide polymorphism (SNP)-array analysis, and high-throughput sequencing of the...
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