Article

Mitochondrial leakage and mtDNA damage trigger early immune response in Inclusion Body Myositis

2024-08-07

Abstract excerpt

Polymyositis with mitochondrial pathology (PM-Mito) was first identified in 1997 as a subtype of idiopathic inflammatory myopathy. Recent findings demonstrated significant molecular similarities between PM-Mito and Inclusion Body Myositis (IBM), suggesting a trajectory from early to late IBM and prompting the inclusion of PM-Mito as an IBM precursor (early IBM) within the IBM spectrum. Both PM-Mito and IBM show mi...

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Literature Corpus work: e79363a9-9657-565a-90ab-7c8abda6acb2
DOI: 10.1101/2024.08.05.606624

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