Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A local antigen-driven humoral response is present in the inflammatory myopathies.

Journal of immunology (Baltimore, Md. : 1950) - 1 Jan 2007

Bradshaw Elizabeth M, Orihuela Ana, McArdel Shannon L, Salajegheh Mohammad, Amato Anthony A, Hafler David A, Greenberg Steven A, O'Connor Kevin C

Abstract excerpt

The inflammatory myopathies are putative autoimmune disorders characterized by muscle weakness and the presence of intramuscular inflammatory infiltrates. Although inclusion body myositis and polymyositis have been characterized as cytotoxic CD8(+) T cell-mediated diseases, we recently demonstrated high frequencies of CD138(+) plasma cells in the inflamed muscle tissue of patients with these diseases. To gain a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibody Formation
Share to B-Lymphocyte Subsets

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, Immunoglobulin Heavy Chain

Share to Immunoglobulin Switch Region

Share to Microdissection

Share to Myositis

Share to Receptors, Antigen, B-Cell

Share to Syndecan-1

Source

Identifiers

PMID: 17182595
DOI: 10.4049/jimmunol.178.1.547

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A local antigen-driven humoral response is present in the inflammatory myopathies.PMID 17182595Read ↗

The V(H) repertoire and clonal diversification of B cells in inflammatory myopathies.Semantic proximity Read ↗

Local immunoglobulin expression in myositis is associated with interferon gamma signaling and correlates with disease activitySemantic proximity Read ↗

Spatial transcriptomics reveals mechanism of autoimmunity driven by internalized autoantibodiesSemantic proximity Read ↗

Deciphering the clinical presentations, pathogenesis, and treatment of the idiopathic inflammatory myopathies.Semantic proximity Read ↗

Pathogenic autoantibody internalization in myositisSemantic proximity Read ↗

Transcriptome Profiling of Immune Cell Types in Peripheral Blood Reveals Common and Specific Pathways Involved in the Pathogenesis of Myositis‐Specific Antibody‐Positive Inflammatory MyopathiesSemantic proximity Read ↗

Pathogenic aspects of dermatomyositis, polymyositis and overlap myositis.Semantic proximity Read ↗

An update on pathogenic mechanisms of inflammatory myopathiesSemantic proximity Read ↗

High-Resolution Spatial Transcriptomics Reveals Interferon-Associated Immune Niches and Antigen Presentation Programs in Inclusion Body MyositisSemantic proximity Read ↗

The Genetics of Autoimmune MyositisSemantic proximity Read ↗

Distinct Cytokine and Cytokine Receptor Expression Patterns Characterize Different Forms of MyositisSemantic proximity Read ↗

Immunohistochemical Phenotype of T Cells Invading Muscle in Inclusion Body Myositis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.