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Article

Inclusion Body Myositis: Clonal Expansions of Muscle‐Infiltrating T Cells Persist Over Time

21 Jul 2003

Abstract excerpt

Inclusion body myositis (IBM) is a chronic inflammatory myopathy. The muscle histology is characterized by infiltration of T cells, which invade and apparently destroy muscle fibres. This study was performed to investigate whether predominant clones of muscle-infiltrating T cells are identical in different muscles and whether they persist over time in IBM. By reverse transcriptase-polymerase chain reaction, 25...

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PMID: 12869141
DOI: 10.1046/j.1365-3083.2003.01251.x

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