Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mitochondrial damage is associated with an early immune response in inclusion body myositis

7 Apr 2025

Abstract excerpt

Polymyositis with mitochondrial pathology (PM-Mito) was first identified in 1997 as a subtype of idiopathic inflammatory myopathy. Recent findings demonstrated significant molecular similarities between PM-Mito and inclusion body myositis (IBM), suggesting a trajectory from early to late IBM and prompting the inclusion of PM-Mito as an IBM precursor (early IBM) within the IBM spectrum. Both PM-Mito and IBM show...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cutaneous lymphoproliferative disorders research
Share to Inflammatory Myopathies and Dermatomyositis
Share to Systemic Sclerosis and Related Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40193586
DOI: 10.1093/brain/awaf118

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mitochondrial damage is associated with an early immune response in inclusion body myositisPMID 40193586Read ↗

Mitochondrial leakage and mtDNA damage trigger early immune response in Inclusion Body MyositisSemantic proximity Read ↗

The Emerging Role of Mitochondrial Dysfunction in the Pathogenesis of Idiopathic Inflammatory MyopathiesSemantic proximity Read ↗

Sporadic Inclusion Body Myositis: An Acquired Mitochondrial Disease with ExtrasSemantic proximity Read ↗

NLRP3 Inflammasome Activation and Altered Mitophagy Are Key Pathways in Inclusion Body MyositisSemantic proximity Read ↗

Human induced pluripotent stem cell-derived myotubes to model inclusion body myositisSemantic proximity Read ↗

Mitochondrial and inflammatory changes in sporadic inclusion body myositis.Semantic proximity Read ↗

Mitochondrial DNA variants in inclusion body myositis characterized by deep sequencingSemantic proximity Read ↗

Cell type mapping of inflammatory muscle diseases highlights selective myofiber vulnerability in inclusion body myositisSemantic proximity Read ↗

A window into intracellular events in myositis through subcellular proteomicsSemantic proximity Read ↗

Mitochondrial pathology in inclusion body myositisSemantic proximity Read ↗

Immune and myodegenerative pathomechanisms in inclusion body myositisSemantic proximity Read ↗

MODERN ASPECTS OF ETIOPATHOGENESIS, DIAGNOSIS, CLINICAL COURSE AND TREATMENT OF SPORADIC INCLUSION BODY MYOSITIS.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.