Article
The association of folate pathway and DNA repair polymorphisms with susceptibility to childhood acute lymphoblastic leukemia.
Gene - 15 May 2015
Goričar Katja, Erčulj Nina, Faganel Kotnik Barbara, Debeljak Maruša, Hovnik Tinka, Jazbec Janez, Dolžan Vita
Abstract excerpt
Genetic factors may play an important role in susceptibility to childhood acute lymphoblastic leukemia (ALL). The aim of our study was to evaluate the associations of genetic polymorphisms in folate pathway and DNA repair genes with susceptibility to ALL. In total, 121 children with ALL and 184 unrelated healthy controls of Slovenian origin were genotyped for 14 polymorphisms in seven genes of folate pathway,...
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