Acute lymphoblastic leukemia and genetic variations in BHMT gene: Case-control study and computational characterization.

doi:10.3233/CBM-160186

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Article

Acute lymphoblastic leukemia and genetic variations in BHMT gene: Case-control study and computational characterization.

Cancer biomarkers : section A of Disease markers - 4 Jul 2017

Bellampalli Ravishankara, Vohra Manik, Sharma Kashish, Bhaskaranand Nalini, Bhat Kamalakshi G, Prasad Krishna, Sharma Anu R, Satyamoorthy Kapaettu, Rai Padmalatha S

Abstract excerpt

BACKGROUND: Remethylation of homocysteine is catalyzed by B12 dependent methionine synthase (MTR) in all types of cells and by B12 non-dependent betaine homocysteine methyltransferase (BHMT) in liver and kidney cells. Of many etiologies of cancer, an unexplored area is the variations of genes implicated in methylation reaction. OBJECTIVE: The study evaluated the association of BHMT (rs3733890) with acute...

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Identifiers

PMID: 28582843
DOI: 10.3233/CBM-160186
PMCID: PMC13020743

Genes

BHMT
MTR

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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