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Article

The 9p21 locus does not affect risk of coronary artery disease through induction of type 1 interferons.

Journal of the American College of Cardiology - 8 Oct 2013

Erridge Clett, Gracey Jay, Braund Peter S, Samani Nilesh J

Abstract excerpt

OBJECTIVES: The study objective was to determine whether the coronary artery disease (CAD)-associated genotype at chromosome 9p21 modulates basal or induced expression of type I interferons (IFN-I). BACKGROUND: The mechanism responsible for the association between common variants in chromosome 9p21.3 and CAD remains unclear. It has been reported that the CAD risk locus is rich in enhancer-like elements and that...

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Identifiers

PMID: 23933542
DOI: 10.1016/j.jacc.2013.07.031

Genes

CAD
CXCL10

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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