Variant on 9p21 is strongly associated with coronary artery disease but lacks association with myocardial infarction and disease severity in a population in Western India.

doi:10.1016/j.arcmed.2011.09.003

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Article

Variant on 9p21 is strongly associated with coronary artery disease but lacks association with myocardial infarction and disease severity in a population in Western India.

Archives of medical research - 1 Aug 2011

Bhanushali Aparna Amarendra, Parmar Neha, Contractor Aashish, Shah Vijay T, Das Bibhu R

Abstract excerpt

BACKGROUND AND AIMS: Coronary artery disease (CAD) is the leading cause of death worldwide, especially so in Indians. Recently, genome-wide studies have implicated SNPs in the 58 kb region of chromosome 9p21 to be associated with CAD. In the current study we evaluated the association of single nucleotide polymorphism (SNP) rs10757278 at the 9p21 locus with CAD in a population from Western India. METHODS:...

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PMID: 21925557
DOI: 10.1016/j.arcmed.2011.09.003

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