Article
9p21 and the genetic revolution for coronary artery disease.
Clinical chemistry - 1 Jan 2012
Roberts Robert, Stewart Alexandre F R
Abstract excerpt
BACKGROUND: It has long been recognized that 50% of the susceptibility for coronary artery disease (CAD) is due to predisposing genetic factors. Comprehensive prevention is likely to require knowledge of these genetic factors. CONTENT: Using a genomewide association study (GWAS), the Ottawa Heart Genomic Study and the deCODE group simultaneously identified the first genetic risk variant, at chromosome 9p21. The...
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