Article
Independent association of the variant rs1333049 at the 9p21 locus and coronary heart disease.
Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology - 1 Jun 2011
Mendonça Isabel, dos Reis Roberto Palma, Pereira Andreia, Café Hugo, Serrão Marco, Sousa Ana Célia, Freitas Ana Isabel, Guerra Graça, Freitas Sónia, Freitas Carolina, Ornelas Ilídio, Brehm António, Araújo José Jorge
Abstract excerpt
INTRODUCTION: Recent genome-wide association studies have identified single-nucleotide polymorphisms (SNPs) at the 9p21 locus as risk factors for coronary artery disease (CAD). Among them, the SNP rs1333049 has demonstrated a consistent association with CAD, which has been successfully replicated in several populations. AIM: To investigate whether the SNP rs1333049 located on the 9p21 chromosome is an independent...
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