Article
Haplotypes on 9p21 modify the risk for coronary artery disease among Indians.
DNA and cell biology - 1 Feb 2011
AshokKumar Manickaraj, Emmanuel Cyril, Dhandapany Perundurai S, Rani Deepa Selvi, SaiBabu Ramineni, Cherian Kootturathu Mammen, Thangaraj Kumarasamy
Abstract excerpt
The chromosomal region 9p21 has been reported to be associated with myocardial infarction, coronary artery disease (CAD), diabetes, and many other related multifactorial diseases in humans. Although the genome-wide association studies have identified a limited number of single-nucleotide polymorphisms (SNPs) at 9p21 for CAD risk, the role of flanking SNPs has not been studied so far. Therefore, in the present...
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