Effect of 9p21 genetic variation on coronary heart disease is not modified by other risk markers. The Atherosclerosis Risk in Communities (ARIC) Study.

doi:10.1016/j.atherosclerosis.2012.08.007

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Effect of 9p21 genetic variation on coronary heart disease is not modified by other risk markers. The Atherosclerosis Risk in Communities (ARIC) Study.

Atherosclerosis - 1 Oct 2012

Folsom Aaron R, Nambi Vijay, Pankow James S, Tang Weihong, Farbakhsh Kian, Yamagishi Kazumasa, Boerwinkle Eric

Abstract excerpt

OBJECTIVE: To determine whether the 9p21 SNP association with coronary heart disease is modified by other classical or novel risk markers. METHODS: The 9p21 SNP (rs10757274) and multiple risk markers were measured in the Atherosclerosis Risk in Communities Study, and incident coronary disease events were ascertained. Effect modification (interaction) of the 9p21 SNP with risk markers was tested in Cox...

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PMID: 22935634
DOI: 10.1016/j.atherosclerosis.2012.08.007
PMCID: PMC3459136

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