Article
Clinical implication of the BRAFV600E mutation in papillary thyroid carcinoma.
World journal of surgical oncology - 20 May 2013
Kim Yong-Seok, Kim Jeong-Soo, Bae Ja-Seong, Park Woo-Chan
Abstract excerpt
BACKGROUND: The BRAFV600E mutation is the most common genetic alteration in papillary thyroid carcinoma (PTC). In recent studies, the BRAFV600E mutation has been associated with poor clinicopathological characteristics, such as lymph node metastasis, extrathyroidal extension, and advanced stage. However, other studies have failed to establish an association between the BRAFV600E mutation and clinicopathological...
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