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Article

Clinicopathologic significance of BRAF V600E mutation in papillary carcinomas of the thyroid: a meta-analysis.

Cancer - 1 Jul 2007

Lee Ju-Han, Lee Eung-Seok, Kim Young-Sik

Abstract excerpt

BACKGROUND: Numerous studies have investigated the clinical significance of BRAF mutation in papillary thyroid carcinoma (PTC). However, there have been conflicting data on the usefulness of BRAF mutation as a prognostic marker of PTC. To address this controversy, the frequency of the BRAF mutation and the associations between BRAF mutation and clinicopathologic parameters in PTC were evaluated by meta-analysis....

Topics

Adult
Amino Acid Substitution
Carcinoma, Papillary
Female
Humans
Lymphatic Metastasis
Male
Middle Aged
Mutation
Neoplasm Staging
Proto-Oncogene Proteins B-raf
Thyroid Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 17520704
DOI: 10.1002/cncr.22754

Genes

BRAF

Variants

Provenance

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