Article
Complement alternative pathway genetic variation and Dengue infection in the Thai population.
Clinical and experimental immunology - 1 Nov 2013
Kraivong R, Vasanawathana S, Limpitikul W, Malasit P, Tangthawornchaikul N, Botto M, Screaton G R, Mongkolsapaya J, Pickering M C
Abstract excerpt
Dengue disease is a mosquito-borne infection caused by Dengue virus. Infection may be asymptomatic or variably manifest as mild Dengue fever (DF) to the most severe form, Dengue haemorrhagic fever (DHF). Mechanisms that influence disease severity are not understood. Complement, an integral component of the immune system, is activated during Dengue infection and the degree of activation increases with disease...
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