Article
Association of FCN2 polymorphisms and Ficolin-2 levels with dengue fever in Vietnamese patients.
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases - 1 Jun 2020
Giang Ngo Truong, Tong Hoang Van, Nghia Trinh Huu, Hung Hoang Vu, Anh Do Tuan, Nam Le Van, Mao Can Van, Giang Nguyen Truong, Thanh Le Dinh, Son Ho Anh, Velavan Thirumalaisamy P, Do Quyet, Toan Nguyen Linh
Abstract excerpt
BACKGROUND AND OBJECTIVE: The human ficolin-2, encoded by FCN2, recognizes pathogen-associated acetylated residues on their cell surfaces and activates the lectin complement cascade. This study aimed to investigate the contribution of human ficolin-2 and the functional FCN2 genetic variants in dengue virus (DENV) infection and in clinical progression. METHODS: FCN2 genetic polymorphisms in the promoter, intron 7...
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