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Article

Alternative Complement Pathway Deregulation Is Correlated with Dengue Severity

25 Aug 2009

Abstract excerpt

BACKGROUND: The complement system, a key component that links the innate and adaptive immune responses, has three pathways: the classical, lectin, and alternative pathways. In the present study, we have analyzed the levels of various complement components in blood samples from dengue fever (DF) and dengue hemorrhagic fever (DHF) patients and found that the level of complement activation is associated with disease...

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PMID: 19707565
DOI: 10.1371/journal.pone.0006782

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