Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

HLA and other gene associations with dengue disease severity.

Current topics in microbiology and immunology - 1 Jan 2010

Stephens H A F

Abstract excerpt

Large case control gene association studies have been performed on cohorts of dengue virus (DENV) infected patients identified in mainland Southeast Asia, South Asia and the Caribbean. Candidate genes that have shown statistically significant associations with DENV disease severity encode HLA molecules, cell receptors for IgG (FcGII), vitamin D and ICAM3 (DCSIGN or CD209), pathogen recognition molecules such as...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, Human Platelet
Share to Asia, Southeastern
Share to Caribbean Region

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dengue

Share to Dengue Virus

Share to Lectins, C-Type

Share to Mannose-Binding Lectin

Share to Receptors, IgG

Source

Identifiers

PMID: 19802581
DOI: 10.1007/978-3-642-02215-9_8

Genes

ABO
ICAM3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

HLA and other gene associations with dengue disease severity.PMID 19802581Read ↗

Host genetics and dengue fever.Semantic proximity Read ↗

Major Histocompatibility Complex Class I Chain-Related A and B (MICA and MICB) Gene, Allele, and Haplotype Associations With Dengue Infections in Ethnic Thais.Semantic proximity Read ↗

HLA-A and -B allele associations with secondary dengue virus infections correlate with disease severity and the infecting viral serotype in ethnic Thais.Semantic proximity Read ↗

Dengue and dengue haemorrhagic fever: implications of host genetics.Semantic proximity Read ↗

Identification of genetic variants associated with dengue or West Nile virus disease: a systematic review and meta-analysis.Semantic proximity Read ↗

Genetic variants of MICB and PLCE1 and associations with the laboratory features of dengue.Semantic proximity Read ↗

Defining the influence of HLA polymorphisms and T cell phenotype and function in dengue disease pathogenesisSemantic proximity Read ↗

Genetic association study of interferon lambda 3, CD27, and human leukocyte antigen-DPB1 with dengue severity in Thailand.Semantic proximity Read ↗

Single nucleotide polymorphisms in candidate genes and dengue severity in children: a case-control, functional and meta-analysis study.Semantic proximity Read ↗

Host genetic susceptibility to severe dengue infectionSemantic proximity Read ↗

Mini-review: Can non-human leucocyte antigen genes determine susceptibility to severe dengue syndromes?Semantic proximity Read ↗

Genome-wide association study identifies susceptibility loci for dengue shock syndrome at MICB and PLCE1.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.