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Article

Complement protein levels and MBL2 polymorphisms are associated with dengue and disease severity.

Scientific reports - 10 Sept 2020

Giang Ngo Truong, van Tong Hoang, Quyet Do, Hoan Nghiem Xuan, Nghia Trinh Huu, Nam Nguyen Minh, Hung Hoang Vu, Anh Do Tuan, Van Mao Can, Son Ho Anh, Meyer Christian G, Velavan Thirumalaisamy P, Toan Nguyen Linh

Abstract excerpt

The complement system may be crucial during dengue virus infection and progression to severe dengue. This study investigates the role of MBL2 genetic variants and levels of MBL in serum and complement proteins in Vietnamese dengue patients. MBL2 genotypes (- 550L/H, MBL2 codon 54), MBL2 diplotypes (XA/XO, YA/XO) and MBL2 haplotypes (LXPB, HXPA, XO) were associated with dengue in the study population. The levels...

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Identifiers

PMID: 32913345
DOI: 10.1038/s41598-020-71947-2
PMCID: PMC7484760

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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