Article
Complement factor H gene (CFH) polymorphisms C-257T, G257A and haplotypes are associated with protection against severe dengue phenotype, possible related with high CFH expression.
Human immunology - 1 Sept 2013
Pastor André F, Rodrigues Moura Laís, Neto José W D, Nascimento Eduardo J M, Calzavara-Silva Carlos E, Gomes Ana Lisa V, Silva Ana Maria da, Cordeiro Marli T, Braga-Neto Ulisses, Crovella Sergio, Gil Laura H V G, Marques Ernesto T A, Acioli-Santos Bartolomeu
Abstract excerpt
Four genetic polymorphisms located at the promoter (C-257T) and coding regions of CFH gene (exon 2 G257A, exon 14 A2089G and exon 19 G2881T) were investigated in 121 dengue patients (DENV-3) in order to assess the relationship between allele/haplotypes variants and clinical outcomes. A statistica...
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