Article
Lack of association between DRD2 and OPRM1 genotypes and adiposity.
International journal of obesity (2005) - 1 May 2014
Hardman C A, Rogers P J, Timpson N J, Munafò M R
Abstract excerpt
BACKGROUND: Dopaminergic and opioid systems are both involved in food intake and appetite control. The dopamine D2 receptor gene (DRD2) and the μ-opioid receptor gene (OPRM1) therefore represent plausible candidates for association with obesity. OBJECTIVE: Previous studies of these variants have yielded inconsistent findings, which are likely due to insufficient statistical power. The aim of the current study was...
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