The Taq IA and Ser311 Cys polymorphisms in the dopamine D2 receptor gene and obesity.

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Article

The Taq IA and Ser311 Cys polymorphisms in the dopamine D2 receptor gene and obesity.

Diabetes, nutrition & metabolism - 1 Feb 2003

Southon A, Walder K, Sanigorski A M, Zimmet P, Nicholson G C, Kotowicz M A, Collier G

Abstract excerpt

Dopamine D2 receptors (DRD2) in the central nervous system are involved in the regulation of feeding. It remains to be elucidated if mutations in the DRD2 gene contribute to the development of obesity. The aim of the present study was to investigate whether the Taq IA and Ser311Cys polymorphisms in the DRD2 gene are associated with obesity in Nauruan and Australian subjects. Subjects were selected based on...

Topics

Adult
Aged
Aged, 80 and over
Australia
Body Mass Index
Female
Genotype
Humans
Male
Middle Aged
Obesity
Point Mutation
Polymerase Chain Reaction
Polymorphism, Genetic
Polymorphism, Restriction Fragment Length
Receptors, Dopamine D2

Source

Open in PubMed

Identifiers

PMID: 12848308

Genes

DRD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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