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Article

DRD2: Bridging the Genome and Ingestive Behavior.

Trends in cognitive sciences - 1 May 2017

Sun Xue, Luquet Serge, Small Dana M

Abstract excerpt

Recent work highlights the importance of genetic variants that influence brain structure and function in conferring risk for polygenic obesity. The neurotransmitter dopamine (DA) has a pivotal role in energy balance by integrating metabolic signals with circuits supporting cognitive, perceptual, and appetitive functions that guide feeding. It has also been established that diet and obesity alter DA signaling,...

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Topics

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Share to Alpha-Ketoglutarate-Dependent Dioxygenase FTO
Share to Dopamine
Share to Gene-Environment Interaction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Genetic Predisposition to Disease

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Share to Protein Serine-Threonine Kinases

Share to Receptors, Dopamine D2

Source

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Identifiers

PMID: 28372879
DOI: 10.1016/j.tics.2017.03.004
PMCID: PMC5745142

Genes

DRD2
FTO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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