Article
Association of dopamine D2 receptor polymorphisms Ser311Cys and TaqIA with obesity or type 2 diabetes mellitus in Pima Indians.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity - 1 Oct 2000
Jenkinson C P, Hanson R, Cray K, Wiedrich C, Knowler W C, Bogardus C, Baier L
Abstract excerpt
OBJECTIVES: To investigate whether (a) variants within the dopamine D2 receptor gene (DRD2) are associated with obesity and type 2 diabetes in Pima Indians, and (b) whether variation in this gene could be responsible for previously observed linkage to these phenotypes, at chromosome location 11q23-24, in this population. DESIGN: Two single nucleotide polymorphisms (SNPs), Ser311Cys and TaqIA, within the DRD2 gene...
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