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Article

β2-adrenergic receptor Thr164Ile polymorphism, obesity, and diabetes: comparison with FTO, MC4R, and TMEM18 polymorphisms in more than 64,000 individuals.

The Journal of clinical endocrinology and metabolism - 1 Jun 2012

Thomsen Mette, Dahl Morten, Tybjærg-Hansen Anne, Nordestgaard Børge G

Abstract excerpt

CONTEXT: The β(2)-adrenergic receptor (ADRB2) influences regulation of energy balance by stimulating catecholamine-induced lipolysis in adipose tissue. The rare functional ADRB2rs1800888(Thr164Ile) polymorphism could therefore influence risk of obesity and subsequently diabetes. OBJECTIVE: We tested the hypothesis that the ADRB2rs1800888(Thr164Ile) polymorphism associates with risk of obesity and diabetes and...

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Source

Identifiers

PMID: 22466342
DOI: 10.1210/jc.2011-3282

Genes

FTO
TMEM18
ADRB2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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