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Article

NF-kappaB activation is required for adaptive cardiac hypertrophy.

Cardiovascular research - 1 Dec 2009

Zelarayan Laura, Renger Anke, Noack Claudia, Zafiriou Maria-Patapia, Gehrke Christina, van der Nagel Roel, Dietz Rainer, de Windt Leon, Bergmann Martin W

Abstract excerpt

AIMS: We have previously shown that cardiac-specific inhibition of NF-kappaB attenuates angiotensin II (AngII)-induced left ventricular (LV) hypertrophy in vivo. We now tested whether NF-kappaB inhibition is able to block LV remodelling upon chronic pressure overload and chronic AngII stimulation...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19620128
DOI: 10.1093/cvr/cvp237

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19620128-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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